Research Guide
GHK-Cu: A Research Guide
GHK-Cu is a naturally occurring copper tripeptide present in human plasma that declines with age. It is studied for its unusually broad gene-expression effects across tissue repair, antioxidant defense, and anti-inflammatory pathways.
Sources
Pickart et al., Biomolecules 2015; Pickart and Margolina, Biomolecules 2018. For research use only. Not approved by the FDA. Not medical advice.
Mechanism
Genome analysis in cited research confirms simultaneous activation of more than 4,000 genes linked to tissue remodeling, DNA repair, and stem cell activation, alongside suppression of over 2,000 genes linked to inflammation and aging. The copper ion is also essential to lysyl oxidase function, the enzyme responsible for properly cross-linking collagen and elastin fibers during tissue repair.
Reconstitution & Storage
This compound ships as a lyophilized powder. Reconstitute with bacteriostatic water before use, and use the calculator on our FAQ page to determine concentration and draw volume.
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Referenced Research Protocols
Wound-healing and hair follicle studies cited below used topical and injectable research models depending on the tissue studied. This guide summarizes published findings, not usage directions.