Semaglutide research vial
Weight LossAppetite

Semaglutide

5mg

Semaglutide activates GLP-1 receptors to regulate appetite and glucose, with outcomes documented across more than 17,000 trial participants. It sustains an average 15% body weight reduction past two years and is the first compound in its class shown to reduce major cardiovascular events in a controlled trial.

Included free with every order

Bacteriostatic reconstitution solution and sterile dosing needles are included, a $30+ value, always included. Most suppliers charge extra. We never do.

Purity

99.4%

Form

Lyophilized powder

Storage

-20°C

Includes

Solution + needles

Research use only. Not for human consumption. Need help reconstituting? Use our dosing calculator.

Research Outcomes

What The Clinical Data Shows

Based on published peer-reviewed literature. Not medical claims.

15%

Average body weight reduction across STEP trials

20%

Reduction in major cardiovascular events, SELECT trial

17,600+

Total participants across all major published trials

Food preference shift. Neuroimaging showed reduced activation of brain reward centers in response to high-calorie food cues, indicating a shift in food preference rather than simple appetite suppression.

Cardiovascular outcome. The SELECT trial (17,604 participants with cardiovascular disease, no diabetes) showed a 20% reduction in heart attack, stroke, and cardiovascular death, independent of weight loss.

Sustained at two years. STEP 5 documented 15.2% weight loss maintained at 104 weeks, suggesting a shift in the body's weight set point rather than temporary suppression.

Secondary outcomes. Sleep apnea events fell by up to 61% in one trial arm, with measurable improvements in knee pain and physical function beyond what weight loss predicts.

Research context. All findings are from peer-reviewed literature. Not FDA-approved. Sold for research purposes only. Results in research settings may vary. Not medical advice.

Read the full Semaglutide research guide →